High prevalence of uric acid calculi in diabetic stone formers.
نویسندگان
چکیده
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منابع مشابه
Renal ammonium excretion after an acute acid load: blunted response in uric acid stone formers but not in patients with type 2 diabetes.
Idiopathic uric acid nephrolithiasis is characterized by elevated urinary net acid excretion and insufficient buffering by ammonium, resulting in excessively acidic urine and titration of the relatively soluble urate anion to insoluble uric acid. Patients with type 2 diabetes have similar changes in urinary pH, net acid excretion, and ammonium in 24-h urine collections at baseline, even after c...
متن کاملOverall, the Proportion of Uric Acid Stones Was 2.2 Times
higher in diabetic than in non-diabetic stone formers, but the difference was strikingly more marked in women than in men with a ratio of 3.8 vs 1.7 (P1⁄4 0.003). It was shown recently that the metabolic syndrome presently affects >40% of the population aged 60 years in the US [4], which is in keeping with the observation that uric acid nephrolithiasis was highly prevalent in our diabetic stone...
متن کاملA comparison of the metabolic profiles of diabetic and non-diabetic uric acid stone formers.
INTRODUCTION The aim of this study was to compare the metabolic profiles of diabetic and non-diabetic patients with uric acid stones to understand whether preventive strategies should be tailored to reflect different causative factors. METHODS The results of the metabolic evaluation of patients with uric acid stones identified prospectively from the Metabolic Stone Clinic at St. Joseph's Hosp...
متن کاملUric Acid Nephrolithiasis: A Systemic Metabolic Disorder.
Uric acid nephrolithiasis is characteristically a manifestation of a systemic metabolic disorder. It has a prevalence of about 10% among all stone formers, the third most common type of kidney stone in the industrialized world. Uric acid stones form primarily due to an unduly acid urine; less deciding factors are hyperuricosuria and a low urine volume. The vast majority of uric acid stone forme...
متن کامل[Oral purine loading test for latent metabolic disorders of uric acid in patients with calcium containing upper urinary calculi].
For the detection of metabolic disorders of uric acid in upper urolithiasis, an oral purine loading test was performed in 78 patients with calcium-containing calculi, 5 patients with uric acid calculi, and 34 stone free subjects. From the results of the normal subject group, the criteria of hyperuricemia, latent hyperuricemia, hyperuricosuria and latent hyperuricosuria were proposed. In calcium...
متن کاملThe diurnal variation in urine acidification differs between normal individuals and uric acid stone formers
Many biological functions follow circadian rhythms driven by internal and external cues that synchronize and coordinate organ physiology to diurnal changes in the environment and behavior. Urinary acid-base parameters follow diurnal patterns and it is thought these changes are due to periodic surges in gastric acid secretion. Abnormal urine pH is a risk factor for specific types of nephrolithia...
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ورودعنوان ژورنال:
- Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
دوره 20 2 شماره
صفحات -
تاریخ انتشار 2005